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Synonyms: ALD-518 | ALD518 | BMS-945429
Compound class: Antibody
Comment: Clazakizumab is an investigational, aglycosylated, humanized (from a rabbit parental antibody) monoclonal antibody targeting interleukin-6, with anti-inflammatory potential .
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. BLAST peptide sequence analysis reveals identical matches with peptides claimed in patent US8062864 . Results presented in the patent show that the preferred antibodies block interaction of IL-6 with the IL-6 receptor, but no precise binding affinity data is provided.
|International Nonproprietary Names|
|ALD-518 | ALD518 | BMS-945429|
|GtoPdb PubChem SID||315661274|
|Search PubMed clinical trials||clazakizumab|
|Search PubMed titles||clazakizumab|
|Search PubMed titles/abstracts||clazakizumab|