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Microtubule associated serine/threonine kinase-like

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Target not currently curated in GtoImmuPdb

Target id: 1514

Nomenclature: Microtubule associated serine/threonine kinase-like

Abbreviated Name: MASTL

Family: MAST family

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 879 10p12.1 MASTL microtubule associated serine/threonine kinase like
Mouse - 865 2 A3 Mastl microtubule associated serine/threonine kinase-like
Rat - 866 17q12.3 Mastl microtubule associated serine/threonine kinase-like
Previous and Unofficial Names Click here for help
GWL | GWLlGwl | Serine/threonine-protein kinase greatwall | THC2 | microtubule associated serine/threonine kinase-like
Database Links Click here for help
Alphafold
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Orphanet
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 2.7.11.1
Immuno Process Associations
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 1 GO processes, IEA only
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GO:1904668 positive regulation of ubiquitin protein ligase activity IEA
Clinically-Relevant Mutations and Pathophysiology Click here for help
Disease:  Thrombocytopenia 2; THC2
Synonyms: Autosomal thrombocytopenia with normal platelets [Orphanet: ORPHA168629]
Thrombocytopenia [Disease Ontology: DOID:1588]
Disease Ontology: DOID:1588
OMIM: 188000
Orphanet: ORPHA168629

How to cite this page

MAST family: Microtubule associated serine/threonine kinase-like. Last modified on 27/01/2015. Accessed on 23/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1514.