X-prolyl aminopeptidase 1 | M24: Methionyl aminopeptidase | IUPHAR/BPS Guide to PHARMACOLOGY

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X-prolyl aminopeptidase 1

Target not currently curated in GtoImmuPdb

Target id: 1578

Nomenclature: X-prolyl aminopeptidase 1

Family: M24: Methionyl aminopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 666 10q25.3 XPNPEP1 X-prolyl aminopeptidase 1
Mouse - 666 19 D2 Xpnpep1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Rat - 623 1q55 Xpnpep1 X-prolyl aminopeptidase 1
Previous and Unofficial Names
Aminopeptidase P 1 | aminoacylproline aminopeptidase | cytoplasmic aminopeptidase P | sAmp | soluble aminopeptidase P | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | X-prolyl aminopeptidase (aminopeptidase P) 1
Database Links
Specialist databases
MEROPS M24.009 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
apstatin Hs Inhibition 4.7 pIC50 1
pIC50 4.7 (IC50 2.1x10-5 M) [1]


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1. Maggiora LL, Orawski AT, Simmons WH. (1999) Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme. J. Med. Chem., 42 (13): 2394-402. [PMID:10395480]

How to cite this page

M24: Methionyl aminopeptidase: X-prolyl aminopeptidase 1. Last modified on 18/09/2015. Accessed on 12/11/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1578.