Quaternary Structure: Complexes

Interleukin-10 receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	578	11q23.3	IL10RA	interleukin 10 receptor subunit alpha
Mouse	1	575	9 24.84 cM	Il10ra	interleukin 10 receptor, alpha
Rat	-	-		Il10ra	interleukin 10 receptor subunit alpha

Previous and Unofficial Names

interleukin 10 receptor | CD210 | Interleukin-10 α | interleukin 10 receptor, alpha

Database Links
Alphafold	Q13651 (Hs), Q61727 (Mm)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL4804254 (Hs)
Ensembl Gene	ENSG00000110324 (Hs), ENSMUSG00000032089 (Mm), ENSRNOG00000016308 (Rn)
Entrez Gene	3587 (Hs), 16154 (Mm), 117539 (Rn)
Human Protein Atlas	ENSG00000110324 (Hs)
KEGG Gene	hsa:3587 (Hs), mmu:16154 (Mm), rno:117539 (Rn)
OMIM	146933 (Hs)
Pharos	Q13651 (Hs)
UniProtKB	Q13651 (Hs), Q61727 (Mm)
Wikipedia	IL10RA (Hs)

Download all structure-activity data for this target as a CSV file

Agonists
Key to terms and symbols		Click column headers to sort
Ligand Sp. Action Value Parameter Reference IL-10 {Sp: Human} Hs Agonist 9.7 – 10.3 pEC50 1 ⤷ pEC50 9.7 – 10.3 (EC50 2x10-10 – 5x10-11 M) [1]

Immunopharmacology Comments

Interleukin 10 receptor, α subunit is a component of the functional IL-10 receptor heterodimer.

Immuno Process Associations

Immuno Process:  Cytokine production & signalling

Immuno Process:  Antigen presentation