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Interleukin 10 receptor, β subunit

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 1728

Nomenclature: Interleukin 10 receptor, β subunit

Family: IL-10 receptor family

Quaternary Structure: Complexes
Interleukin-10 receptor
Interleukin-22α1/10β heteromer
Interferon-λ receptor 1
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 325 21q22.11 IL10RB interleukin 10 receptor subunit beta
Mouse 1 349 16 52.87 cM Il10rb interleukin 10 receptor, beta
Rat - - Il10rb interleukin 10 receptor subunit beta
Previous and Unofficial Names Click here for help
CRF2-4 | CRFB4 | IL-10R2 | Il10rb | Interleukin-10 β | interleukin 10 receptor, beta | interleukin 10 receptor
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
Immunopharmacology Comments
Interleukin 10 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 10 and 22 and for interferons λ1, λ2 and λ3.
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 1 GO processes
GO:0006954 inflammatory response TAS
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 3 GO processes, IEA only
GO:0004896 cytokine receptor activity IBA
GO:0004920 interleukin-10 receptor activity IBA
GO:0019221 cytokine-mediated signaling pathway IBA

How to cite this page

IL-10 receptor family: Interleukin 10 receptor, β subunit. Last modified on 06/04/2017. Accessed on 24/06/2022. IUPHAR/BPS Guide to PHARMACOLOGY,