Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	417	1p36.31	TNFRSF25	TNF receptor superfamily member 25
Mouse	-	-		Tnfrsf25	tumor necrosis factor receptor superfamily, member 25
Rat	-	-		Tnfrsf25	TNF receptor superfamily member 25

Previous and Unofficial Names

apoptosis-mediating receptor DR3 | apoptosis-mediating receptor TRAMP | death domain receptor 3 | WSL-1 | WSL-LR | tumor necrosis factor receptor superfamily, member 25 | APO-3 | DDR3 | TNFRSF12 | TR3 | tumor necrosis factor receptor superfamily

Database Links
Alphafold	Q93038 (Hs)
Ensembl Gene	ENSG00000215788 (Hs), ENSMUSG00000024793 (Mm), ENSRNOG00000021814 (Rn)
Entrez Gene	8718 (Hs), 85030 (Mm), 500592 (Rn)
Human Protein Atlas	ENSG00000215788 (Hs)
KEGG Gene	hsa:8718 (Hs), mmu:85030 (Mm), rno:500592 (Rn)
OMIM	603366 (Hs)
Pharos	Q93038 (Hs)
UniProtKB	Q93038 (Hs)
Wikipedia	TNFRSF25 (Hs)

Natural/Endogenous Ligands
TL1A {Sp: Human}

Adaptor proteins (Human)

TRADD

Other Binding Ligands
Key to terms and symbols		Click column headers to sort
Ligand Sp. Action Value Parameter Reference TL1A {Sp: Human} Hs - - - ⤷

Immunopharmacology Comments

In the absence of any other exogenous signals, activation of DR3 causes proliferation of FoxP3+ regulatory T cells [1].

Immuno Process Associations

Immuno Process:  Cytokine production & signalling