Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	2986	3q21.1-q21.2	KALRN	kalirin RhoGEF kinase
Mouse	-	2964	16 B3	Kalrn	kalirin, RhoGEF kinase
Rat	-	2959	11q22	Kalrn	kalirin, RhoGEF kinase

Previous and Unofficial Names

cyclin B1 | DUET | HAPIP | huntingtin-associated protein interacting protein (duo) | PAM COOH-terminal interactor protein 10 | P-CIP10 | TRAD | kalirin | kalirin, RhoGEF kinase

Database Links
Alphafold	O60229 (Hs), A2CG49 (Mm), P97924 (Rn)
BRENDA	2.7.11.1
CATH/Gene3D	2.30.29.30, 2.60.40.10, 3.40.525.10
ChEMBL Target	CHEMBL2176786 (Rn)
Ensembl Gene	ENSG00000160145 (Hs), ENSMUSG00000061751 (Mm), ENSRNOG00000001706 (Rn)
Entrez Gene	8997 (Hs), 545156 (Mm), 84009 (Rn)
Human Protein Atlas	ENSG00000160145 (Hs)
KEGG Enzyme	2.7.11.1
KEGG Gene	hsa:8997 (Hs), mmu:545156 (Mm), rno:84009 (Rn)
OMIM	604605 (Hs)
Pharos	O60229 (Hs)
RefSeq Nucleotide	NM_001024660 (Hs), NM_001164268 (Mm), NM_032062 (Rn)
RefSeq Protein	NP_001019831 (Hs), NP_001157740 (Mm), NP_114451 (Rn)
UniProtKB	O60229 (Hs), A2CG49 (Mm), P97924 (Rn)
Wikipedia	KALRN (Hs)

Selected 3D Structures
	Description:  Solution structure of rat Kalirin N-terminal SH3 domain PDB Id:  1U3O Resolution:  0.0Å Species:  Human References:  1

Enzyme Reaction
EC Number: 2.7.11.1

Clinically-Relevant Mutations and Pathophysiology
Disease:  Coronary heart disease, susceptibility to, 5 Synonyms: Coronary heart disease [Disease Ontology: DOID:3393] Disease Ontology: DOID:3393 OMIM: 608901