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PTEN induced kinase 1

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Target not currently curated in GtoImmuPdb

Target id: 2161

Nomenclature: PTEN induced kinase 1

Abbreviated Name: PINK1

Family: NKF2 family

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 581 1p36.12 PINK1 PTEN induced kinase 1
Mouse 1 580 4 D3 Pink1 PTEN induced putative kinase 1
Rat - 257 5 q36 Pink1 PTEN induced kinase 1
Previous and Unofficial Names Click here for help
brpk | Parkinson disease (autosomal recessive) 6
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:
Immuno Process Associations
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 4 GO processes
GO:0016567 protein ubiquitination IMP
GO:0031396 regulation of protein ubiquitination IDA
GO:0031398 positive regulation of protein ubiquitination ISS
GO:0051443 positive regulation of ubiquitin-protein transferase activity TAS
Clinically-Relevant Mutations and Pathophysiology Click here for help
Disease:  Parkinson disease 6, autosomal recessive early-onset; PARK6
Synonyms: Parkinson's disease [Disease Ontology: DOID:14330]
Young adult-onset Parkinsonism [Orphanet: ORPHA2828]
Disease Ontology: DOID:14330
OMIM: 605909
Orphanet: ORPHA2828

How to cite this page

NKF2 family: PTEN induced kinase 1. Last modified on 18/09/2018. Accessed on 04/02/2023. IUPHAR/BPS Guide to PHARMACOLOGY,