RIO kinase 3
Target not currently curated in GtoImmuPdb
Target id: 2188
Nomenclature: RIO kinase 3
Abbreviated Name: RIOK3
Family: RIO3 subfamily
Annotation status:
Annotated and awaiting review. Please contact us if you can help with reviewing.
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Contents:
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | - | 519 | 18q11.2 | RIOK3 | RIO kinase 3 | |
| Mouse | - | 519 | 18 A2 | Riok3 | RIO kinase 3 | |
| Rat | - | 519 | 18 p13 | Riok3 | RIO kinase 3 | |
| Previous and Unofficial Names |
| SUDD |
| Database Links |
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| BRENDA | 2.7.11.1 |
| ChEMBL Target | CHEMBL5659 (Hs) |
| Ensembl Gene | ENSG00000101782 (Hs), ENSMUSG00000024404 (Mm), ENSRNOG00000023376 (Rn) |
| Entrez Gene | 8780 (Hs), 66878 (Mm), 361293 (Rn) |
| Human Protein Atlas | ENSG00000101782 (Hs) |
| KEGG Enzyme | 2.7.11.1 |
| KEGG Gene | hsa:8780 (Hs), mmu:66878 (Mm), rno:361293 (Rn) |
| OMIM | 603579 (Hs) |
| RefSeq Nucleotide | NM_003831 (Hs), NM_024182 (Mm), NM_001108423 (Rn) |
| RefSeq Protein | NP_003822 (Hs), NP_077144 (Mm), NP_001101893 (Rn) |
| UniProtKB | O14730 (Hs), Q9DBU3 (Mm) |
| Wikipedia | RIOK3 (Hs) |
| Enzyme Reaction |
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| DiscoveRx KINOMEscan® screen |
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A screen of 72 inhibitors against 456 human kinases. Quantitative data were derived using DiscoveRx KINOMEscan® platform. http://www.discoverx.com/services/drug-discovery-development-services/kinase-profiling/kinomescan Reference: 1-2 |
 
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| Target used in screen: RIOK3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Displaying the top 10 most potent ligands View all ligands in screen » | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
References
1. Davis MI, Hunt JP, Herrgard S, Ciceri P, Wodicka LM, Pallares G, Hocker M, Treiber DK, Zarrinkar PP. (2011) Comprehensive analysis of kinase inhibitor selectivity. Nat. Biotechnol., 29 (11): 1046-51. [PMID:22037378]
2. Wodicka LM, Ciceri P, Davis MI, Hunt JP, Floyd M, Salerno S, Hua XH, Ford JM, Armstrong RC, Zarrinkar PP et al.. (2010) Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. Chem. Biol., 17 (11): 1241-9. [PMID:21095574]
How to cite this page
RIO3 subfamily: RIO kinase 3. Last modified on 18/08/2014. Accessed on 23/07/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2188.
