Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	418	4q13.2	TMPRSS11D	transmembrane serine protease 11D
Mouse	1	417	5 E1	Tmprss11d	transmembrane protease, serine 11d
Rat	1	417	14p21	Tmprss11d	transmembrane serine protease 11D

Previous and Unofficial Names

adrenal secretory serine protease | airway trypsin-like protease | Asp | AST | AT | transmembrane protease, serine 11d | transmembrane protease | transmembrane protease, serine 11D

Database Links
Specialist databases
MEROPS	S01.047 (Hs)
Other databases
Alphafold	O60235 (Hs), Q8VHK8 (Mm), Q8VHJ4 (Rn)
BRENDA	3.4.21.-
CATH/Gene3D	3.30.70.960
ChEMBL Target	CHEMBL1795138 (Hs)
Ensembl Gene	ENSG00000153802 (Hs), ENSMUSG00000061259 (Mm), ENSRNOG00000055991 (Rn)
Entrez Gene	9407 (Hs), 231382 (Mm), 64565 (Rn)
Human Protein Atlas	ENSG00000153802 (Hs)
KEGG Enzyme	3.4.21.-
KEGG Gene	hsa:9407 (Hs), mmu:231382 (Mm), rno:64565 (Rn)
OMIM	605369 (Hs)
Pharos	O60235 (Hs)
RefSeq Nucleotide	NM_004262 (Hs), NM_145561 (Mm), NM_001033652 (Rn), NM_022630 (Rn)
RefSeq Protein	NP_004253 (Hs), NP_663536 (Mm), NP_072152 (Rn), NP_001028824 (Rn)
UniProtKB	O60235 (Hs), Q8VHK8 (Mm), Q8VHJ4 (Rn)
Wikipedia	TMPRSS11D (Hs)

Enzyme Reaction
EC Number: 3.4.21.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference inhibitor 1 [Colombo et al., 2012] Hs Inhibition 8.1 pKi 1 ⤷ pKi 8.1 (Ki 8.4x10-9 M) [1] compound 5 [PMID: 21741839] Hs Inhibition 7.7 pKi 2 ⤷ pKi 7.7 (Ki 1.9x10-8 M) [2]

Immuno Process Associations

Immuno Process:  Barrier integrity