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tryptase gamma 1

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Target not currently curated in GtoImmuPdb

Target id: 2425

Nomenclature: tryptase gamma 1

Family: S1: Chymotrypsin

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 321 16p13.3 TPSG1 tryptase gamma 1
Mouse 1 311 17 12.53 cM Tpsg1 tryptase gamma 1
Rat - 311 10q12 Tpsg1 tryptase gamma 1
Previous and Unofficial Names Click here for help
tryptase gamma I | Prss31 | Tmt | transmembrane tryptase | tryptase gamma II
Database Links Click here for help
Specialist databases
MEROPS S01.028 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number: 3.4.21.-

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
WX-UK1 Small molecule or natural product ? Inhibition 5.2 pKi 1
pKi 5.2 (Ki 6.3x10-6 M) [1]


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1. Stürzebecher J, Vieweg H, Steinmetzer T, Schweinitz A, Stubbs MT, Renatus M, Wikström P. (1999) 3-Amidinophenylalanine-based inhibitors of urokinase. Bioorg Med Chem Lett, 9 (21): 3147-52. [PMID:10560742]

How to cite this page

S1: Chymotrypsin: tryptase gamma 1. Last modified on 29/07/2015. Accessed on 24/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY,