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ubiquitin specific peptidase 5

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Target not currently curated in GtoImmuPdb

Target id: 2431

Nomenclature: ubiquitin specific peptidase 5

Family: C19: Ubiquitin-specific protease

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 858 12p13 USP5 ubiquitin specific peptidase 5
Mouse - 858 6 59.17 cM Usp5 ubiquitin specific peptidase 5 (isopeptidase T)
Rat - 858 4q42 Usp5 ubiquitin specific peptidase 5
Previous and Unofficial Names Click here for help
deubiquitinating enzyme 5 | IsoT | ubiquitin carboxy terminal hydrolase T | ubiquitin carboxyl-terminal hydrolase 5 | ubiquitin specific protease 5 | ubiquitin thioesterase 5 | ubiquitin thiolesterase 5 | Ucht | ubiquitin specific peptidase 5 (isopeptidase T)
Database Links Click here for help
Specialist databases
MEROPS C19.001 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
vialinin A Small molecule or natural product Hs Inhibition 5.4 pKi 1
pKi 5.4 (Ki 4x10-6 M) [1]
Immuno Process Associations
Immuno Process:  Cellular signalling


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1. Okada K, Ye YQ, Taniguchi K, Yoshida A, Akiyama T, Yoshioka Y, Onose J, Koshino H, Takahashi S, Yajima A et al.. (2013) Vialinin A is a ubiquitin-specific peptidase inhibitor. Bioorg Med Chem Lett, 23 (15): 4328-31. [PMID:23791076]

How to cite this page

C19: Ubiquitin-specific protease: ubiquitin specific peptidase 5. Last modified on 28/07/2015. Accessed on 11/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY,