Top ▲
Gene and Protein Information ![]() |
||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 2511 | 17q25.3 | FASN | fatty acid synthase | |
Mouse | - | 2504 | 11 84.56 cM | Fasn | fatty acid synthase | |
Rat | - | 2505 | 10q32.3 | Fasn | fatty acid synthase |
Previous and Unofficial Names ![]() |
FAS |
Database Links ![]() |
|
BRENDA | 2.3.1.85 |
CATH/Gene3D | 3.40.47.10, 1.10.1470.20 |
ChEMBL Target | CHEMBL4158 (Hs), CHEMBL1795189 (Mm), CHEMBL3783 (Rn) |
DrugBank Target | P49327 (Hs) |
Ensembl Gene | ENSG00000169710 (Hs), ENSMUSG00000025153 (Mm), ENSRNOG00000045636 (Rn) |
Entrez Gene | 2194 (Hs), 14104 (Mm), 50671 (Rn) |
Human Protein Atlas | ENSG00000169710 (Hs) |
KEGG Enzyme | 2.3.1.85 |
KEGG Gene | hsa:2194 (Hs), mmu:14104 (Mm), rno:50671 (Rn) |
OMIM | 600212 (Hs) |
Pharos | P49327 (Hs) |
RefSeq Nucleotide | NM_004104 (Hs), NM_007988 (Mm), NM_017332 (Rn) |
RefSeq Protein | NP_004095 (Hs), NP_032014 (Mm), NP_059028 (Rn) |
SynPHARM | 82454 (in complex with GSK2194069) |
UniProtKB | P49327 (Hs), P19096 (Mm), P12785 (Rn) |
Wikipedia | FASN (Hs) |
Selected 3D Structures ![]() |
|||||||||||||
![]() |
|
Enzyme Reaction ![]() |
||||
|
Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||
|
Immuno Process Associations | |||||||||||||||
|
|||||||||||||||
|
2.3.1.- Acyltransferases: fatty acid synthase. Last modified on 13/08/2015. Accessed on 06/03/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2608.