Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	262	19q13.33	KLK1	kallikrein 1
Mouse	-	261	7 28.74 cM	Klk1	kallikrein 1
Rat	-	261	1q22	Klk1	kallikrein 1

Previous and Unofficial Names

renal/pancreas/salivary kallikrein

Database Links
Specialist databases
MEROPS	S01.160 (Hs)
Other databases
Alphafold	P06870 (Hs), P15947 (Mm), P00758 (Rn)
BRENDA	3.4.21.35
ChEMBL Target	CHEMBL2319 (Hs)
Ensembl Gene	ENSG00000167748 (Hs), ENSMUSG00000063903 (Mm), ENSRNOG00000068378 (Rn)
Entrez Gene	3816 (Hs), 16612 (Mm), 24523 (Rn)
Human Protein Atlas	ENSG00000167748 (Hs)
KEGG Enzyme	3.4.21.35
KEGG Gene	hsa:3816 (Hs), mmu:16612 (Mm), rno:24523 (Rn)
OMIM	147910 (Hs)
Pharos	P06870 (Hs)
RefSeq Nucleotide	NM_002257 (Hs), NM_010639 (Mm), NM_031523 (Rn)
RefSeq Protein	NP_002248 (Hs), NP_034769 (Mm), NP_113711 (Rn)
UniProtKB	P06870 (Hs), P15947 (Mm), P00758 (Rn)
Wikipedia	KLK1 (Hs)

Enzyme Reaction
EC Number: 3.4.21.35

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference example 131 [WO2009133348] Hs Inhibition 9.3 pIC50 1 ⤷ pIC50 9.3 (IC50 5.4x10-10 M) [1]