kallikrein 1 | S1: Chymotrypsin | IUPHAR/BPS Guide to PHARMACOLOGY

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kallikrein 1

Target not currently curated in GtoImmuPdb

Target id: 2865

Nomenclature: kallikrein 1

Family: S1: Chymotrypsin

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 262 19q13.3 KLK1 kallikrein 1
Mouse - 261 7 B4 Klk1 kallikrein 1
Rat - 265 1q22 Klk1 kallikrein 1
Previous and Unofficial Names
renal/pancreas/salivary kallikrein
Database Links
Specialist databases
MEROPS S01.160 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
example 131 [WO2009133348] Hs Inhibition 9.3 pIC50 1
pIC50 9.3 (IC50 5.4x10-10 M) [1]


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1. Evans DM, Allan CE, Horton J, Rooker DP. (2009) Aminopyridine derivatives. Patent number: WO2009133348. Assignee: Vantia Limited.. Priority date: 29/04/2008. Publication date: 05/11/2009.

How to cite this page

S1: Chymotrypsin: kallikrein 1. Last modified on 22/09/2015. Accessed on 18/10/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2865.