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kallikrein 1

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Target not currently curated in GtoImmuPdb

Target id: 2865

Nomenclature: kallikrein 1

Family: S1: Chymotrypsin

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 262 19q13.33 KLK1 kallikrein 1
Mouse - 261 7 28.74 cM Klk1 kallikrein 1
Rat - 261 1q22 Klk1 kallikrein 1
Previous and Unofficial Names Click here for help
renal/pancreas/salivary kallikrein
Database Links Click here for help
Specialist databases
MEROPS S01.160 (Hs)
Other databases
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.4.21.35

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
example 131 [WO2009133348] Small molecule or natural product Immunopharmacology Ligand Hs Inhibition 9.3 pIC50 1
pIC50 9.3 (IC50 5.4x10-10 M) [1]

References

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1. Evans DM, Allan CE, Horton J, Rooker DP. (2009) Aminopyridine derivatives. Patent number: WO2009133348. Assignee: Vantia Limited.. Priority date: 29/04/2008. Publication date: 05/11/2009.

How to cite this page

S1: Chymotrypsin: kallikrein 1. Last modified on 06/12/2019. Accessed on 23/07/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2865.