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CD209 molecule

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Immunopharmacology Ligand target has curated data in GtoImmuPdb

Target id: 2930

Nomenclature: CD209 molecule

Abbreviated Name: DC-SIGN

Family: C-type lectin-like receptors (CLRs)

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 404 19p13.2 CD209 CD209 molecule
Gene and Protein Information Comments
A number of splice variants, encoding different protein isoforms of human CD209 have been identified. The mouse has five CD209 homologs and there are no rat homologs.
Previous and Unofficial Names Click here for help
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
RefSeq Nucleotide
RefSeq Protein
Immunopharmacology Comments
DC-SIGN is a pathogen-recognition receptor involved in initiating the primary immune response to various viral and bacterial pathogens, as well as antigen presentation and initiation of the adaptive immune response.
Cell Type Associations
Immuno Cell Type:  Macrophages & monocytes
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process:  Antigen presentation
Immuno Process:  T cell (activation)
Immuno Process:  Immune regulation
Immuno Process:  Chemotaxis & migration
Immuno Process:  Cellular signalling
Immuno Process:  Barrier integrity
Immuno Process:  B cell (activation)
General Comments
DC-SIGN (CD209) is a pathogen-recognition receptor expressed on the surface of immature dendritic cells.

How to cite this page

C-type lectin-like receptors (CLRs): CD209 molecule. Last modified on 16/07/2020. Accessed on 14/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY,