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Taste 2 receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The composition and stoichiometry of bitter taste receptors is not yet established. Bitter receptors appear to separate into two groups, with very restricted ligand specificity or much broader responsiveness. For example, T2R5 responded to cycloheximide, but not 10 other bitter compounds [2], while T2R14 responded to at least eight different bitter tastants, including (-)-α-thujone and picrotoxinin [1].

Specialist database BitterDB contains additional information on bitter compounds and receptors [6].

Receptors

676
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TAS2R1 C Show summary »

TAS2R3 C Show summary »

TAS2R4 C Show summary »

TAS2R5 C Show summary »

TAS2R7 C Show summary »

TAS2R8 C Show summary »

TAS2R9 C Show summary »

TAS2R10 C Show summary »

TAS2R13 C Show summary »

TAS2R14 C Show summary »

TAS2R16 C Show summary »

TAS2R19 C Show summary »

TAS2R20 C Show summary »

TAS2R30 C Show summary »

TAS2R31 C Show summary »

TAS2R38 C Show summary »

TAS2R39 C Show summary »

TAS2R40 C Show summary »


Target Id 676
Nomenclature TAS2R40
Previous and unofficial names GPR60 | T2R40 | G protein-coupled receptor 60 | taste receptor, type 2, member 40
Genes TAS2R40 (Hs)
Ensembl ID ENSG00000221937 (Hs)
UniProtKB AC P59535 (Hs)
BitterDB 40 (Hs)
Principal transduction -

TAS2R41 C Show summary »

TAS2R42 C Show summary »

TAS2R43 C Show summary »

TAS2R45 C Show summary »

TAS2R46 C Show summary »

TAS2R50 C Show summary »

TAS2R60 C Show summary »

Further reading

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References

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How to cite this family page

Database page citation:

Taste 2 receptors. Accessed on 17/08/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=117.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. Br J Pharmacol. 176 Suppl 1:S27-S156.