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M12: Astacin/Adamalysin C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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ADAM (A Disintegrin And Metalloproteinase domain containing proteins) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

ADAMTS (with thrombospondin motifs) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

Enzymes

1661
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ADAM2 Show summary »

ADAM7 Show summary »

ADAM8 Show summary » More detailed page go icon to follow link

ADAM9 Show summary » More detailed page go icon to follow link

ADAM10 Show summary » More detailed page go icon to follow link

ADAM11 Show summary »

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ADAM15 Show summary »


Target Id 1661
Nomenclature ADAM15
Previous and unofficial names Metalloprotease RGD disintegrin protein | MDC15 | CRII-7 | tMDCVI | a disintegrin and metallopeptidase domain 15 (metargidin)
Genes ADAM15 (Hs), Adam15 (Mm), Adam15 (Rn)
Ensembl ID ENSG00000143537 (Hs), ENSMUSG00000028041 (Mm), ENSRNOG00000020590 (Rn)
UniProtKB AC Q13444 (Hs), O88839 (Mm), Q9QYV0 (Rn)

ADAM17 Show summary » More detailed page go icon to follow link

ADAM18 Show summary »

ADAM19 Show summary »

ADAM20 Show summary »

ADAM21 Show summary »

ADAM22 Show summary »

ADAM23 Show summary »

ADAM28 Show summary »

ADAM29 Show summary »

ADAM30 Show summary »

ADAM32 Show summary »

ADAM33 Show summary » More detailed page go icon to follow link

ADAMTS1 Show summary » More detailed page go icon to follow link

ADAMTS2 Show summary »

ADAMTS3 Show summary »

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ADAMTS5 Show summary » More detailed page go icon to follow link

ADAMTS6 Show summary »

ADAMTS7 Show summary »

ADAMTS8 Show summary »

ADAMTS9 Show summary »

ADAMTS10 Show summary »

ADAMTS12 Show summary »

ADAMTS13 Show summary »

ADAMTS14 Show summary »

ADAMTS15 Show summary »

ADAMTS16 Show summary »

ADAMTS17 Show summary »

ADAMTS18 Show summary »

ADAMTS19 Show summary »

ADAMTS20 Show summary »

bone morphogenetic protein 1 Show summary » More detailed page go icon to follow link

Comments

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References

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How to cite this family page

Database page citation:

M12: Astacin/Adamalysin. Accessed on 07/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=739.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.