ChEMBL ligand: CHEMBL33 (Cravit, DR-3355, Evoxil, Floxacin, Iquix, Levaquin, Levofloxacin, Levofloxacin anhydrous, Levofloxacin (as hemihydrate), Levofloxacin hemihydrate, Levofloxacin hydrate, L-ofloxacin, Nofaxin, NSC-758709, Ofloxacin, (s)-, Ofloxacin s-(-)-form, Ofloxacin s-(-)-form hemihydrate, Oftaquix, Quinsair, Quixin, RWJ-25213, Tavanic, Volequin)
DNA gyrase subunit A in Mycobacterium tuberculosis [ChEMBL: CHEMBL4165] [UniProtKB: P9WG47] There should be some charts here, you may need to enable JavaScript!
Multidrug and toxin extrusion/Multidrug and toxin extrusion protein 1 in Human [ChEMBL: CHEMBL1743126] [GtoPdb: 1216] [UniProtKB: Q96FL8] There should be some charts here, you may need to enable JavaScript!
Plasmodium falciparum [ChEMBL: CHEMBL364] There should be some charts here, you may need to enable JavaScript!
Replicase polyprotein 1ab in Middle East respiratory syndrome-related coronavirus (isolate UnitedKingdom/H123990006/2012) (Betacoronavirus England 1) (Humancoronavirus EMC) [ChEMBL: CHEMBL4295557] [UniProtKB: K9N7C7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
DNA gyrase subunit A in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4165] [UniProtKB: P9WG47]
ChEMBL	Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase A	B	4.28	pIC50	52000	nM	IC50	Antimicrob Agents Chemother (2010) 54: 3478-3480 [PMID:20516287]
Multidrug and toxin extrusion/Multidrug and toxin extrusion protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743126] [GtoPdb: 1216] [UniProtKB: Q96FL8]
ChEMBL	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	B	4.75	pIC50	17900	nM	IC50	J Med Chem (2013) 56: 781-795 [PMID:23241029]
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocytes after 72 hrs by SYBR Green-1 staining based fluorescence assay	F	4.7	pIC50	>20000	nM	IC50	Eur J Med Chem (2017) 139: 22-47 [PMID:28800458]
Replicase polyprotein 1ab in Middle East respiratory syndrome-related coronavirus (isolate UnitedKingdom/H123990006/2012) (Betacoronavirus England 1) (Humancoronavirus EMC) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4295557] [UniProtKB: K9N7C7]
ChEMBL	MERS_3CL Pro protease inhibition IC50 by FRET kind of response from peptide substrate	F	5.12	pIC50	7600	nM	IC50	Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]