compound 11 [PMID: 41150938] [Ligand Id: 14261] activity data from GtoPdb

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  • carbonic anhydrase 1 in Human [GtoPdb: 2597] [UniProtKB: P00915]
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  • histone deacetylase 3 in Human [GtoPdb: 2617] [UniProtKB: O15379]
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  • histone deacetylase 8 in Human [GtoPdb: 2619] [UniProtKB: Q9BY41]
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  • carbonic anhydrase 12 in Human [GtoPdb: 2747] [UniProtKB: O43570]
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  • carbonic anhydrase 9 in Human [GtoPdb: 3055] [UniProtKB: Q16790]
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  • carbonic anhydrase 2 in Human [GtoPdb: 3092] [UniProtKB: P00918]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
carbonic anhydrase 1 in Human [GtoPdb: 2597] [UniProtKB: P00915]
GtoPdb - - 6.84 pKi 144.6 nM Ki J Med Chem (2025) : [PMID:41150938]
histone deacetylase 3 in Human [GtoPdb: 2617] [UniProtKB: O15379]
GtoPdb - - 6.68 pIC50 210 nM IC50 J Med Chem (2025) : [PMID:41150938]
histone deacetylase 8 in Human [GtoPdb: 2619] [UniProtKB: Q9BY41]
GtoPdb - - 5.44 pIC50 3600 nM IC50 J Med Chem (2025) : [PMID:41150938]
carbonic anhydrase 12 in Human [GtoPdb: 2747] [UniProtKB: O43570]
GtoPdb - - 8.14 pKi 7.3 nM Ki J Med Chem (2025) : [PMID:41150938]
carbonic anhydrase 9 in Human [GtoPdb: 3055] [UniProtKB: Q16790]
GtoPdb - - 7.51 pKi 31 nM Ki J Med Chem (2025) : [PMID:41150938]
carbonic anhydrase 2 in Human [GtoPdb: 3092] [UniProtKB: P00918]
GtoPdb - - 8.13 pKi 7.4 nM Ki J Med Chem (2025) : [PMID:41150938]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.