Synonyms: R-95867 | R95867
Compound class:
Synthetic organic
Comment: Tacapenem (R-95867) is a β-lactam class antibacterial. It exhibits broad-spectrum antibacterial activity and it is highly stable to β-lactamases. An ester-type prodrug of R-95867, CS-834 (tacapenem pivoxil for oral administration), has been described [2].
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Bioactivity Comments |
The in vivo effecacy of oral CS-834 against systemic infections in mice caused by various bacteria was protective, and correlated well with the in vitro activity of R-95867 [1]. |