Synonyms: R-95867 | R95867
Compound class:
Synthetic organic
Comment: Tacapenem (R-95867) is a β-lactam class antibacterial. It exhibits broad-spectrum antibacterial activity and it is highly stable to β-lactamases. An ester-type prodrug of R-95867, CS-834 (tacapenem pivoxil for oral administration), has been described [2].
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References |
1. Sakagawa E, Otsuki M, Oh T, Nishino T, Ou T. (1998)
In-vitro and in-vivo antibacterial activities of CS-834, a new oral carbapenem. J Antimicrob Chemother, 42 (4): 427-37. [PMID:9818740] |
2. Yamaguchi K, Domon H, Miyazaki S, Tateda K, Ohno A, Ishii K, Matsumoto T, Furuya N. (1998)
In vitro and in vivo antibacterial activities of CS-834, a new oral carbapenem. Antimicrob Agents Chemother, 42 (3): 555-63. [PMID:9517932] |