Synonyms: RBx 7644
Compound class:
Synthetic organic
Comment: Ranbezolid is an oxazolidinone class antibacterial with potent activity against a broad-spectrum of Gram-positive bacterial strains, including methicillin-resistant Staphylococcus aureus (MRSA) [1].
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Bioactivity Comments |
The oxazolidinone class of antibacterials inhibit protein synthesis by blocking function of the bacterial 50S ribosomal subunit. Ranbezolid has been shown to specifically inhibit the bacterial ribosome with an IC50 of 20 μM [2]. The MIC for antibacterial activity against Staphylococcus aureus 562 is 1 μg/ml in vitro [1]. |