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dromostanolone propionate   Click here for help

GtoPdb Ligand ID: 6947

Synonyms: drostanolone | Masteron®
Approved drug
dromostanolone propionate is an approved drug
Compound class: Synthetic organic
Comment: This drug is a synthetic androgen with similar properties to testosterone. Drostanolone is used extensively (and illicitly) by athletes and bodybuilders aiming to build muscle strength and definition.
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Click here for structure editor
Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/). All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 43.37
Molecular weight 360.27
XLogP 5.78
No. Lipinski's rules broken 1

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

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Canonical SMILES CCC(=O)OC1CCC2C1(C)CCC1C2CCC2C1(C)CC(C)C(=O)C2
Isomeric SMILES CCC(=O)O[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)C[C@@H](C)C(=O)C2
InChI InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1
InChI Key NOTIQUSPUUHHEH-UXOVVSIBSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes.
IUPAC Name Click here for help
[(2R,5S,8R,9S,10S,13S,14S,17S)-2,10,13-trimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] propanoate
International Nonproprietary Names Click here for help
INN number INN
1159 drostanolone
Synonyms Click here for help
drostanolone | Masteron®
Database Links Click here for help
CAS Registry No. 58-19-5
ChEMBL Ligand CHEMBL1201048
DrugBank Ligand DB00858
DrugCentral Ligand 965
GtoPdb PubChem SID 178103529
PubChem CID 224004
Search Google for chemical match using the InChIKey NOTIQUSPUUHHEH-UXOVVSIBSA-N
Search Google for chemicals with the same backbone NOTIQUSPUUHHEH
Search PubMed clinical trials drostanolone
Search PubMed titles drostanolone
Search PubMed titles/abstracts drostanolone
UniChem Compound Search for chemical match using the InChIKey NOTIQUSPUUHHEH-UXOVVSIBSA-N
UniChem Connectivity Search for chemical match using the InChIKey NOTIQUSPUUHHEH-UXOVVSIBSA-N
Wikipedia Drostanolone propionate