Ligand id: 10013

Name: AbGn-168H

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
selectin P ligand Hs Antibody Agonist 11.5 pKd - 3
pKd 11.5 (Kd 3x10-12 M) [3]
Description: Kd calculated as the inverse of the Ka (333 nM) presented in the patent reference. Ka was calculated from a competition binding assay that measured displacement of murine anti-PSGL-1 antibody 15A7 by AbGn-168H from purified PSGL-1.