AChE reactivator 2

Ligand id: 10074

Name: AChE reactivator 2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 91.88
Molecular weight 425.17
XLogP 5.39
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
acetylcholinesterase (Cartwright blood group) Hs None - 5.6 pIC50 - 1
pIC50 5.6 (IC50 2.3x10-6 M) [1]
Description: Measuring reactivation of hAChE.