Ligand id: 10159

Name: benidipine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 111.01
Molecular weight 505.22
XLogP 5.41
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Cav1.2 Hs Channel blocker Antagonist 5.3 pIC50 - 1
pIC50 5.3 (IC50 4.9x10-6 M) [1]
Description: Inhibition of human L-type calcium channel Cav1.2 in Xenopus oocyte, measured using 2-electrode voltage-clamp.