Compound class:
Synthetic organic
Comment: RU1968 is a cross-species inhibitor of CatSper Ca2+ channels [1]. It can be used as a chemical probe to elucidate the function of CatSper channels in sperm from different species.
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Bioactivity Comments |
RU1968 abolishes progesterone- and PGE1-induced Ca2+ signals in human sperm [1]. |
Ligand mentioned in the following text fields |
CatSper and Two-Pore channels (TPC) overview |