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Compound class: Synthetic organic
Comment: C2 is a positive allosteric modulator (PAM) that targets CB2 receptors. It has reported antinociceptive efficacy in an animal model of neuropathic pain .
|C2 enhances CP55940 and 2-arachidonoylglycerol-stimulated binding of [35S]GTPγS to CB2 receptors, but it is inactive in the absence of agonist .|
|Selectivity at GPCRs|
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