Ligand id: 1057

Name: GW1100

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 120.98
Molecular weight 520.16
XLogP 6.51
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
FFA1 receptor Hs Antagonist Antagonist 6.0 pIC50 - 1-2
pIC50 6.0 (IC50 1x10-6 M) [1-2]