Compound class:
Synthetic organic
Comment: Noncompetitive Epac1 inhibitor.
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Bioactivity Comments |
Noncompetitive Epac1 inhibitor. Blocks Epac-induced Rap activation and prevents isoprenaline-induced autophagy flux in cardiomyocytes. Has no effect on PKA activity in the presence of cAMP. |
Selectivity at enzymes | ||||||||||||||||||||||||||||||||||
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