UCSF4226

Ligand id: 10667

Name: UCSF4226

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 34.15
Molecular weight 292.02
XLogP 2.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
MT2 receptor Hs Agonist Agonist 8.1 pEC50 - 1
pEC50 8.1 (EC50 7.08x10-9 M) [1]
MT1 receptor Hs Agonist Agonist 6.8 pEC50 - 1
pEC50 6.8 (EC50 1.479x10-7 M) [1]