CGP 71872

Ligand id: 1074

Name: CGP 71872

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 6
Rotatable bonds 16
Topological polar surface area 178.36
Molecular weight 659.1
XLogP 4.26
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
GABAB1 Rn Antagonist Antagonist 8.3 – 8.4 pIC50 - 1
pIC50 8.3 – 8.4 [1]
Ligand mentioned in the following text fields