Synonyms: Apatef® | Cefotan® | ICI-156834 | ICI156834
cefotetan is an approved drug (FDA (1985))
Compound class:
Synthetic organic
Comment: Cefotetan is a semi-synthetic, broad-spectrum, β-lactamase-resistant, second-generation cephalosporin antibacterial. Because of its inhibitory activity towards human aldehyde dehydrogenase, cefotetan produces an effect to ethanol similar to that produced by disulfiram (Antabuse).
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Bioactivity Comments |
MIC for antibacterial activity across a range of Bacteroides spp. range from 4-128 μg/ml in vitro [1-2]. |