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Compound class:
Endogenous peptide in human, mouse or rat
Comment: There is some ambiguity in the literature and on other resources as to the exact chemical structure and stereochemistry of ghrelin. In the absence of a consensus chemical structure, we have chosen not to include an image of the molecule on this ligand entry. However, for representations of the structure please see these CHEBI:75431, CHEMBL425281 and PubChem CID 16133832 entries.
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖
View more information in the IUPHAR Pharmacology Education Project: ghrelin |
| Natural/Endogenous Targets | ||
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| Additional information and targets (data relate to human unless otherwise stated) | ||
| Description | Data | Reference |
| Potency order of endogenous ligands at ghrelin receptor | ghrelin (GHRL, Q9UBU3) = [des-Gln14]ghrelin (GHRL, Q9UBU3) | 1,5 |
| Ligand mentioned in the following text fields |
| Ghrelin receptor overview |
| Ghrelin receptor comments |
