osocimab   Click here for help

GtoPdb Ligand ID: 11366

Synonyms: BAY 1213790 | BAY-1213790 | BAY1213790
Compound class: Antibody
Comment: Osocimab (BAY 1213790) is a fully humanized monoclonal antibody that targets activated Factor XI [1]. It is being investigated for clinical prevention of thrombosis [2].
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Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
coagulation factor XI Hs Antibody Inhibition 8.6 pKd - 1
pKd 8.6 (Kd 2.4x10-9 M) [1]
Description: Binding affinity by SPR