epcoritamab   Click here for help

GtoPdb Ligand ID: 11442

Synonyms: GEN-3013 | GEN3013
Immunopharmacology Ligand
Compound class: Antibody
Comment: Epcoritamab (GEN3013) is a novel CD3ε/CD20 bispecific IgG1 antibody that redirects CD3+ T-cells to CD20 expressing tumour cells [1]. Its Fc domain has been mutated to prevent FcγR and complement binding.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Hs Antibody Binding - - - 1
CD3e Hs Antibody Binding - - - 1