Synonyms: Artedil® | CV-4093 | CV4093 | Franidipine® | Iperten®
manidipine is an approved drug
Compound class:
Synthetic organic
Comment: Manidipine (CV-4093) is dihydropyridine calcium channel blocker.
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Bioactivity Comments |
Manidipine is selective for calcium channels in the vasculature and has no effect on the heart at clinically relevant doses. It inhibits nitrendipine binding to L-type calcium channels derived from rat cerebral cortex (IC50 8.6 nM) [1] |