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Synonyms: MP5D2_CL22A3 | UCB-6114
Compound class:
Antibody
Comment: Ginisortamab (UCB6114) is a human IgG4κ monoclonal antibody that targets the endogenous BMP antagonist peptide gremlin 1. The heavy and light chain peptide sequences of ginisortamab are claimed in UCB Biopharma's patent WO2018115017A2 [1].The patent describes their antibodies as allosteric modulators, whose epitope is distal to the BMP binding site of gremlin 1.
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