INSL3 [A(5-26):B(7-27)]   Click here for help

GtoPdb Ligand ID: 11914

Comment: This is an INSL3 peptide structure with truncated A and B chains [A(5-26):B(7-27)] [1]. It retains comparable activity to the endogenous peptide.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP2 Hs Agonist Agonist 7.8 pKi - 1
pKi 7.8 (Ki 1.6x10-8 M) [1]
Description: Receptor binding
RXFP2 Hs Agonist Agonist 10.0 pEC50 - 1
pEC50 10.0 (EC50 1x10-10 M) [1]
Description: Receptor activation