Synonyms: carbenicillin indanyl | CP-15,464-2 | CP-15464-2 | Geocillin®
carindacillin is an approved drug (FDA (1972))
Compound class:
Synthetic organic
Comment: Carindacillin is a semisynthetic carboxypenicillin belonging to the β-lactam class of antibacterial compounds. It is an orally bioavailable prodrug that is hydrolysed into carbenicillin [1-2].
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Bioactivity Comments |
The spectrum of in vitro antibacterial activity of carindacillin is similar to carbenicillin [1]. Carindacillin is more potent against susceptible Gram-positive bacteria but this is not of clinical significance because of the rapid in vivo metabolism of the prodrug. |