Synonyms: BAY805 | compound 21 [PMID: 36802665]
Compound class:
Synthetic organic
Comment: BAY-805 is a non-covalent ubiquitin-specific protease 21 (USP21) inhibitor [2]. Target engagement by BAY-805 induces NF-κB activation in a cell-based reporter assay, which supports the proposition that inhibiting USP21 will reverse its role in carcinogenesis [1].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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