α-MSH

Ligand id: 1320

Name: α-MSH

Species: Human, Mouse, Rat

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View more information in the IUPHAR Pharmacology Education Project: msh

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
MC1 receptor
MC3 receptor
MC4 receptor
MC5 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
MC5 receptor Hs Agonist Full agonist 6.9 pKd - 2
pKd 6.9 [2]
MC3 receptor Hs Agonist Full agonist 8.0 – 8.4 pKi - 1,3
pKi 8.0 – 8.4 [1,3]
MC4 receptor Hs Agonist Full agonist 7.4 – 8.0 pKi - 1,4
pKi 7.4 – 8.0 [1,4]
MC1 receptor Hs Agonist Full agonist 8.4 pIC50 - 2
pIC50 8.4 [2]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields