Synonyms: compound C9 [WO2020081879A2] | PTC-857 | PTC857
Compound class:
Synthetic organic
Comment: Utreloxastat (PTC-857) is described as a 15-lipoxygenase inhibitor in its INN record. It was developed for potential to treat α-synucleinopathies, tauopathies, ALS and other brain injuries/insults [1].
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Bioactivity Comments |
Inhibits α-synuclein aggregation and disaggregates pre-formed fibrils of human wild-type Tau K18 in vitro [1]. |