MGS0039

Ligand id: 1397

Name: MGS0039

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 109.85
Molecular weight 377.02
XLogP -0.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
mGlu2 receptor Rn Antagonist Antagonist 8.6 – 8.7 pKi - 1-2
pKi 8.6 – 8.7 [1-2]
mGlu3 receptor Rn Antagonist Antagonist 8.3 – 8.4 pKi - 1-2
pKi 8.3 – 8.4 [1-2]