[125I]LTT-SRIF-28   Click here for help

GtoPdb Ligand ID: 2023

Synonyms: 3-[125I](Leu8, D-Trp22, Tyr25)somatostatin-28 | 3-[125I]LTT-SRIF-28 | [125I](Leu8, D-Trp22, Tyr25)-somatostatin-28
 Ligand is labelled  Ligand is radioactive
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Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
SST5 receptor Mm Agonist Full agonist 11.0 pKd - 2
pKd 11.0 [2]
SST2 receptor Hs Agonist Full agonist 9.9 – 10.0 pKd - 5-7
pKd 9.9 – 10.0 [5-7]
SST3 receptor Hs Agonist Full agonist 9.4 – 10.3 pKd - 1,5-6,8
pKd 9.7 – 10.3 [1,6,8]
pKd 9.4 [5]
SST5 receptor Hs Agonist Full agonist 9.2 – 10.5 pKd - 5-6,8
pKd 10.5 [6,8]
pKd 9.2 [5]
SST1 receptor Hs Agonist Full agonist 8.8 – 10.0 pKd - 5-6,8
pKd 10.0 [6,8]
pKd 8.8 [5]
SST2 receptor Rn Agonist Full agonist 9.0 – 9.3 pKd - 3-4
pKd 9.0 – 9.3 (Kd 9.5x10-10 – 4.6x10-10 M) [3-4]
SST4 receptor Hs Agonist Full agonist 8.4 pKd - 5
pKd 8.4 [5]
SST4 receptor Hs Agonist Full agonist 9.6 pIC50 - 6
pIC50 9.6 [6]
Ligand mentioned in the following text fields