[Phe(Me)7]neurokinin B   Click here for help

GtoPdb Ligand ID: 2113

Synonyms: [MePhe7]NKB
Comment: Synthetic analogue of neurokinin B
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
NK3 receptor Mm Agonist Full agonist 9.2 pKi - 3
pKi 9.2 [3]
NK3 receptor Hs Agonist Full agonist 8.7 – 9.6 pKi - 3-4
pKi 8.7 – 9.6 [3-4]
NK2 receptor Hs Agonist Full agonist 6.9 pKi - 4
pKi 6.9 [4]
NK3 receptor Hs Agonist Full agonist 8.9 pEC50 - 1-2
pEC50 8.9 (EC50 1.3x10-9 M) [1-2]