BAY 55-9837

Ligand id: 2269

Name: BAY 55-9837

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
VPAC2 receptor Hs Agonist Agonist 9.4 pEC50 - 1
pEC50 9.4 (EC50 4x10-10 M) [1]
Description: cyclic AMP formation in CHO cells stably expressing recombinant receptor
VPAC1 receptor Hs Agonist Agonist 7.0 pEC50 - 1
pEC50 7.0 (EC50 1x10-7 M) [1]
Description: cyclic AMP formation in CHO cells stably expressing recombinant receptor
VPAC2 receptor Hs Agonist Agonist 7.2 pIC50 - 1
pIC50 7.2 (IC50 6x10-8 M) [1]
Description: inhibition of [125I]-PACAP-27 binding to membranes from CHO cells stably expressing the recombinant receptor
VPAC1 receptor Hs Agonist Agonist 5.1 pIC50 - 1
pIC50 5.1 (IC50 8.7x10-6 M) [1]
Description: inhibition of [125I]-PACAP-27 binding to membranes from CHO cells stably expressing the recombinant receptor
PAC1 receptor Hs Agonist Agonist <5.0 pIC50 - 1
pIC50 <5.0 (IC50 >1x10-5 M) [1]
Description: inhibition of [125I]-PACAP-27 binding to membranes from CHO cells stably expressing the recombinant receptor