BIMU 8

Ligand id: 234

Name: BIMU 8

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 59.27
Molecular weight 342.21
XLogP 2.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT4 receptor Rn Agonist Full agonist 7.1 – 7.8 pKi - 1
pKi 7.1 – 7.8 [1]
5-HT4 receptor Mm Agonist Full agonist 7.4 pKi - 3
pKi 7.4 [3]
5-HT4 receptor Hs Agonist Full agonist 7.3 pKi - 2
pKi 7.3 (Ki 5.01x10-8 M) [2]