L-783483

Ligand id: 2688

Name: L-783483

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 97.86
Molecular weight 487.08
XLogP 7.05
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at nuclear hormone receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Peroxisome proliferator-activated receptor-β/δ Hs Agonist Full agonist 9.0 pKd - 1
pKd 9.0 [1]
Liver X receptor-β Hs Agonist Agonist 8.2 pKd - 2
pKd 8.2 [2]
Liver X receptor-α Hs Agonist Agonist 7.9 pKd - 2
pKd 7.9 [2]
Peroxisome proliferator-activated receptor-γ Hs Agonist Full agonist 7.8 pKi - 1
pKi 7.8 [1]