L-lactic acid   Click here for help

GtoPdb Ligand ID: 2932

Synonyms: (S)-lactate | (S)-lactic acid | L-lactate | lactate
PDB Ligand
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 57.53
Molecular weight 90.03
XLogP -0.59
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES OC(=O)C(O)C
Isomeric SMILES OC(=O)[C@@H](O)C
InChI InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
InChI Key JVTAAEKCZFNVCJ-REOHCLBHSA-N
Natural/Endogenous Targets
Target
HCA1 receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
SMCT2
Monocarboxylate transporter 1
Monocarboxylate transporter 4
SMCT1
Monocarboxylate transporter 2
Monocarboxylate transporter 3
Sialin
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
HCA1 receptor Ligand is endogenous in the given species Mm Agonist Full agonist 2.2 – 2.8 pEC50 - 1,3
pEC50 2.2 – 2.8 [1,3]
HCA1 receptor Ligand is endogenous in the given species Hs Agonist Full agonist 1.3 – 2.9 pEC50 - 1-4
pEC50 1.3 – 2.9 [1-4]
Ligand mentioned in the following text fields